Role of Benzimidazole (Bid) in the δ Opioid Agonist Pseudopeptide H-Dmt-Tic-NH-CH(2)-Bid (UFP-502)

H-Dmt-Tic-NH-CH(2)-Bid (UFP-502) was the first δ opioid agonist prepared from the Dmt-Tic pharmacophore. It showed interesting pharmacological properties, such as stimulation of mRNA BDNF expression, and antidepression. To evaluate the importance of 1H-benzimidazol-2-yl (Bid) in the induction of δ a...

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Hauptverfasser: Salvadori, Severo, Fiorini, Stella, Trapella, Claudio, Porreca, Frank, Davis, Peg, Sasaki^, Yusuke, Ambo, Akihiro, Ewa, D Marczak, Lazarus, Lawrence H., Balboni, Gianfranco
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390930/
https://ncbi.nlm.nih.gov/pubmed/18178091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.12.032
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