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Further Studies on Lead Compounds Containing the Opioid Pharmacophore Dmt-Tic
Opioids containing the Dmt-Tic pharmacophore, especially the δ agonists H-Dmt-Tic-Gly-NH-Ph 1 and H-Dmt-Tic-NH-(S)CH(CH(2)-COOH)-Bid 4 (UFP-512) were evaluated for the influence of the substitution of Gly with aspartic acid, its chirality, and the importance of the – NH-Ph and N(1)H-Bid hydrogens re...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812024/ https://ncbi.nlm.nih.gov/pubmed/18680274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800587e |
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