Further Studies on Lead Compounds Containing the Opioid Pharmacophore Dmt-Tic

Opioids containing the Dmt-Tic pharmacophore, especially the δ agonists H-Dmt-Tic-Gly-NH-Ph 1 and H-Dmt-Tic-NH-(S)CH(CH(2)-COOH)-Bid 4 (UFP-512) were evaluated for the influence of the substitution of Gly with aspartic acid, its chirality, and the importance of the – NH-Ph and N(1)H-Bid hydrogens re...

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Hauptverfasser: Balboni, Gianfranco, Fiorini, Stella, Baldisserotto, Anna, Trapella, Claudio, Sasaki, Yusuke, Ambo, Akihiro, Marczak, Ewa D., Lazarus, Lawrence H., Salvadori, Severo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812024/
https://ncbi.nlm.nih.gov/pubmed/18680274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800587e
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