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Effect of Lysine at C-Terminus of the Dmt-Tic Opioid Pharmacophore
Substitution of Gly with side-chain protected or unprotected Lys in lead compounds containing the opioid pharmacophore Dmt-Tic [H-Dmt-Tic-Gly-NH-CH(2)-Ph, μ agonist / δ antagonist; H-Dmt-Tic-Gly-NH-Ph, μ agonist / δ agonist and H-Dmt-Tic-NH-CH(2)-Bid, δ agonist (Bid = 1H-benzimidazole-2-yl)] yielded...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533050/ https://ncbi.nlm.nih.gov/pubmed/16942034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060741w |
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