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Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G

Potential applications for functional RNAs are rapidly expanding, not only to address functions based on primary nucleotide sequences, but also by RNA aptamer, which can suppress the activity of any target molecule. Aptamers are short DNA or RNA folded molecules that can be selected in vitro on the...

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Autors principals: Miyakawa, Shin, Nomura, Yusuke, Sakamoto, Taiichi, Yamaguchi, Yoshiki, Kato, Koichi, Yamazaki, Satoko, Nakamura, Yoshikazu
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390795/
https://ncbi.nlm.nih.gov/pubmed/18441054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1005808
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