Characterisation of an aptamer against the Runt domain of AML1 (RUNX1) by NMR and mutational analyses

Since the invention of systematic evolution of ligands by exponential enrichment, many short oligonucleotides (or aptamers) have been reported that can bind to a wide range of target molecules with high affinity and specificity. Previously, we reported an RNA aptamer that shows high affinity to the...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Takada, Kenta, Amano, Ryo, Nomura, Yusuke, Tanaka, Yoichiro, Sugiyama, Shigeru, Nagata, Takashi, Katahira, Masato, Nakamura, Yoshikazu, Kozu, Tomoko, Sakamoto, Taiichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794459/
https://ncbi.nlm.nih.gov/pubmed/29435416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12368
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