Conformational plasticity of RNA for target recognition as revealed by the 2.15 Å crystal structure of a human IgG–aptamer complex

Aptamers are short single-stranded nucleic acids with high affinity to target molecules and are applicable to therapeutics and diagnostics. Regardless of an increasing number of reported aptamers, the structural basis of the interaction of RNA aptamer with proteins is poorly understood. Here, we det...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nomura, Yusuke, Sugiyama, Shigeru, Sakamoto, Taiichi, Miyakawa, Shin, Adachi, Hiroaki, Takano, Kazufumi, Murakami, Satoshi, Inoue, Tsuyoshi, Mori, Yusuke, Nakamura, Yoshikazu, Matsumura, Hiroyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995045/
https://ncbi.nlm.nih.gov/pubmed/20675355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq615
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados