Loading...

Conformational plasticity of RNA for target recognition as revealed by the 2.15 Å crystal structure of a human IgG–aptamer complex

Aptamers are short single-stranded nucleic acids with high affinity to target molecules and are applicable to therapeutics and diagnostics. Regardless of an increasing number of reported aptamers, the structural basis of the interaction of RNA aptamer with proteins is poorly understood. Here, we det...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Nomura, Yusuke, Sugiyama, Shigeru, Sakamoto, Taiichi, Miyakawa, Shin, Adachi, Hiroaki, Takano, Kazufumi, Murakami, Satoshi, Inoue, Tsuyoshi, Mori, Yusuke, Nakamura, Yoshikazu, Matsumura, Hiroyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995045/
https://ncbi.nlm.nih.gov/pubmed/20675355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq615
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!