Crystallization and preliminary X-ray diffraction studies of an RNA aptamer in complex with the human IgG Fc fragment

Aptamers, which are folded DNA or RNA molecules, bind to target molecules with high affinity and specificity. An RNA aptamer specific for the Fc fragment of human immunoglobulin G (IgG) has recently been identified and it has been demonstrated that an optimized 24-nucleotide RNA aptamer binds to the...

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Auteurs principaux: Sugiyama, Shigeru, Nomura, Yusuke, Sakamoto, Taiichi, Kitatani, Tomoya, Kobayashi, Asako, Miyakawa, Shin, Takahashi, Yoshinori, Adachi, Hiroaki, Takano, Kazufumi, Murakami, Satoshi, Inoue, Tsuyoshi, Mori, Yusuke, Nakamura, Yoshikazu, Matsumura, Hiroyoshi
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2008
Sujets:
Crystallization Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564881/
https://ncbi.nlm.nih.gov/pubmed/18931441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108028236
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