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Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272

This paper reports the crystallization and preliminary neutron diffraction measurements of HIV-1 protease, a potential target for anti-HIV therapy, complexed with an inhibitor (KNI-272). The aim of this neutron diffraction study is to obtain structural information about the H atoms and to determine...

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Detalhes bibliográficos
Main Authors: Matsumura, Hiroyoshi, Adachi, Motoyasu, Sugiyama, Shigeru, Okada, Shino, Yamakami, Megumi, Tamada, Taro, Hidaka, Koushi, Hayashi, Yoshio, Kimura, Tooru, Kiso, Yoshiaki, Kitatani, Tomoya, Maki, Sho, Yoshikawa, Hiroshi Y., Adachi, Hiroaki, Takano, Kazufumi, Murakami, Satoshi, Inoue, Tsuyoshi, Kuroki, Ryota, Mori, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581681/
https://ncbi.nlm.nih.gov/pubmed/18997326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108029679
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