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The Runt domain of AML1 (RUNX1) binds a sequence-conserved RNA motif that mimics a DNA element
AML1 (RUNX1) is a key transcription factor for hematopoiesis that binds to the Runt-binding double-stranded DNA element (RDE) of target genes through its N-terminal Runt domain. Aberrations in the AML1 gene are frequently found in human leukemia. To better understand AML1 and its potential utility f...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683927/ https://ncbi.nlm.nih.gov/pubmed/23709277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.037879.112 |
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