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RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex
The Notch pathway is a conserved cell-to-cell signaling mechanism, in which extracellular signals are transduced into transcriptional outputs through the nuclear effector CSL. CSL is converted from a repressor to an activator through the formation of the CSL-NotchIC-Mastermind ternary complex. The R...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386923/ https://ncbi.nlm.nih.gov/pubmed/18381292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709501200 |
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