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Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster

In metazoans, the highly conserved Notch pathway drives cellular specification. On receptor activation, the intracellular domain of Notch assembles a transcriptional activator complex that includes the DNA-binding protein CSL, a composite of human C-promoter binding factor 1, Suppressor of Hairless...

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Bibliographic Details
Main Authors: Maier, Dieter, Kurth, Patricia, Schulz, Adriana, Russell, Andrew, Yuan, Zhenyu, Gruber, Kim, Kovall, Rhett A., Preiss, Anette
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164469/
https://ncbi.nlm.nih.gov/pubmed/21737682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-05-0420
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