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Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster

Notch is a conserved signaling pathway that specifies cell fates in metazoans. Receptor-ligand interactions induce changes in gene expression, which is regulated by the transcription factor CBF1/Su(H)/Lag-1 (CSL). CSL interacts with coregulators to repress and activate transcription from Notch targe...

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書誌詳細
出版年:PLoS Biol
主要な著者: Yuan, Zhenyu, Praxenthaler, Heiko, Tabaja, Nassif, Torella, Rubben, Preiss, Anette, Maier, Dieter, Kovall, Rhett A.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942083/
https://ncbi.nlm.nih.gov/pubmed/27404588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002509
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