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Generation of New Hairless Alleles by Genomic Engineering at the Hairless Locus in Drosophila melanogaster

Hairless (H) is the major antagonist within the Notch signalling pathway of Drosophila melanogaster. By binding to Suppressor of Hairless [Su(H)] and two co-repressors, H induces silencing of Notch target genes in the absence of Notch signals. We have applied genomic engineering to create several ne...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Praxenthaler, Heiko, Smylla, Thomas K., Nagel, Anja C., Preiss, Anette, Maier, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598140/
https://ncbi.nlm.nih.gov/pubmed/26448463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140007
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