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In vivo analysis of internal ribosome entry at the Hairless locus by genome engineering in Drosophila

Cell communication in metazoans requires the highly conserved Notch signaling pathway, which is subjected to strict regulation of both activation and silencing. In Drosophila melanogaster, silencing involves the assembly of a repressor complex by Hairless (H) on Notch target gene promoters. We previ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Smylla, Thomas K., Preiss, Anette, Maier, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054391/
https://ncbi.nlm.nih.gov/pubmed/27713501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34881
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