Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless

Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-binding protein CSL. In the absence of signal, a repre...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Praxenthaler, Heiko, Nagel, Anja C., Schulz, Adriana, Zimmermann, Mirjam, Meier, Markus, Schmid, Hannes, Preiss, Anette, Maier, Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438185/
https://ncbi.nlm.nih.gov/pubmed/28475577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006774
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