Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless

Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-binding protein CSL. In the absence of signal, a repre...

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Vydáno v:PLoS Genet
Hlavní autoři: Praxenthaler, Heiko, Nagel, Anja C., Schulz, Adriana, Zimmermann, Mirjam, Meier, Markus, Schmid, Hannes, Preiss, Anette, Maier, Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438185/
https://ncbi.nlm.nih.gov/pubmed/28475577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006774
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