Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless

Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-binding protein CSL. In the absence of signal, a repre...

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Udgivet i:PLoS Genet
Main Authors: Praxenthaler, Heiko, Nagel, Anja C., Schulz, Adriana, Zimmermann, Mirjam, Meier, Markus, Schmid, Hannes, Preiss, Anette, Maier, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438185/
https://ncbi.nlm.nih.gov/pubmed/28475577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006774
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