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Thermodynamic binding analysis of Notch transcription complexes from Drosophila melanogaster

Notch is an intercellular signaling pathway that is highly conserved in metazoans and is essential for proper cellular specification during development and in the adult organism. Misregulated Notch signaling underlies or contributes to the pathogenesis of many human diseases, most notably cancer. Si...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Contreras, Ashley N, Yuan, Zhenyu, Kovall, Rhett A
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420529/
https://ncbi.nlm.nih.gov/pubmed/25650119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2652
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