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Transcriptional Repression in the Notch Pathway: THERMODYNAMIC CHARACTERIZATION OF CSL-MINT (Msx2-INTERACTING NUCLEAR TARGET PROTEIN) COMPLEXES

The Notch pathway is a conserved cell-to-cell signaling mechanism that mediates cell fate decisions in metazoans. Canonical signaling results in changes in gene expression, which is regulated by the nuclear effector of the pathway CSL (CBF1/RBP-J, Su(H), Lag-1). CSL is a DNA binding protein that fun...

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Detalles Bibliográficos
Autores principales: VanderWielen, Bradley D., Yuan, Zhenyu, Friedmann, David R., Kovall, Rhett A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083192/
https://ncbi.nlm.nih.gov/pubmed/21372128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181156
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