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Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA

Notch signaling is a conserved pathway of communication between neighboring cells that results in cell fate specification, and CSL is the universal transcriptional effector of Notch signaling. The Notch intracellular domain translocates to the nucleus after proteolytic release upon Notch extracellul...

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Bibliographic Details
Main Authors: Kovall, Rhett A, Hendrickson, Wayne A
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC516623/
https://ncbi.nlm.nih.gov/pubmed/15297877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600349
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