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Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA

Notch signaling is a conserved pathway of communication between neighboring cells that results in cell fate specification, and CSL is the universal transcriptional effector of Notch signaling. The Notch intracellular domain translocates to the nucleus after proteolytic release upon Notch extracellul...

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Autors principals: Kovall, Rhett A, Hendrickson, Wayne A
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516623/
https://ncbi.nlm.nih.gov/pubmed/15297877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600349
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