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Transcriptional Repression in the Notch Pathway: THERMODYNAMIC CHARACTERIZATION OF CSL-MINT (Msx2-INTERACTING NUCLEAR TARGET PROTEIN) COMPLEXES
The Notch pathway is a conserved cell-to-cell signaling mechanism that mediates cell fate decisions in metazoans. Canonical signaling results in changes in gene expression, which is regulated by the nuclear effector of the pathway CSL (CBF1/RBP-J, Su(H), Lag-1). CSL is a DNA binding protein that fun...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083192/ https://ncbi.nlm.nih.gov/pubmed/21372128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181156 |
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