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Aberrant IgA1 Glycosylation Is Inherited in Familial and Sporadic IgA Nephropathy
IgA nephropathy (IgAN) is a complex trait determined by genetic and environmental factors. Most IgAN patients exhibit a characteristic undergalactosylation of the O-glycans of the IgA1 hinge region, which promotes formation and glomerular deposition of immune complexes. It is not known whether this...
Gorde:
| Egile Nagusiak: | , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society of Nephrology
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386728/ https://ncbi.nlm.nih.gov/pubmed/18272841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007091052 |
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