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Platinum-based inhibitors of amyloid-β as therapeutic agents for Alzheimer's disease
Amelyoid-β peptide (Aβ) is a major causative agent responsible for Alzheimer's disease (AD). Aβ contains a high affinity metal binding site that modulates peptide aggregation and toxicity. Therefore, identifying molecules targeting this site represents a valid therapeutic strategy. To test this...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2383936/ https://ncbi.nlm.nih.gov/pubmed/18463291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800712105 |
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