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Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone

AIM: Clinical use of amiodarone is associated with occasional development of torsade de pointes (TdP). However, preclinical models have failed to demonstrate the proarrhythmic potential of amiodarone. The objective of this study was to reveal and explain the pro- and anti-arrhythmic effects of acute...

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Autores principales: Wu, Lin, Rajamani, Sridharan, Shryock, John C., Li, Hong, Ruskin, Jeremy, Antzelevitch, Charles, Belardinelli, Luiz
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365898/
https://ncbi.nlm.nih.gov/pubmed/18006430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvm069
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