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Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone

AIM: Clinical use of amiodarone is associated with occasional development of torsade de pointes (TdP). However, preclinical models have failed to demonstrate the proarrhythmic potential of amiodarone. The objective of this study was to reveal and explain the pro- and anti-arrhythmic effects of acute...

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Detalhes bibliográficos
Main Authors: Wu, Lin, Rajamani, Sridharan, Shryock, John C., Li, Hong, Ruskin, Jeremy, Antzelevitch, Charles, Belardinelli, Luiz
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365898/
https://ncbi.nlm.nih.gov/pubmed/18006430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvm069
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