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Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine

Pathological conditions linked to imbalances in oxygen supply and demand (for example, ischaemia, hypoxia and heart failure) are associated with disruptions in intracellular sodium ([Na(+)](i)) and calcium ([Ca(2+)](i)) concentration homeostasis of myocardial cells. A decreased efflux or increased i...

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Hlavní autoři: Belardinelli, L, Shryock, J C, Fraser, H
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861317/
https://ncbi.nlm.nih.gov/pubmed/16775092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2005.078790
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