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Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine
BACKGROUND: Quinidine is used to treat atrial fibrillation and ventricular arrhythmias. However, at low concentrations, it can induce torsade de pointes (TdP). OBJECTIVE: The purpose of this study was to examine the role of late sodium current (I(Na)) as a modulator of the arrhythmogenicity of quini...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669543/ https://ncbi.nlm.nih.gov/pubmed/19084812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2008.09.008 |
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