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The arrhythmogenic consequences of increasing late I(Na) in the cardiomyocyte

This review presents the roles of cardiac sodium channel Na(V)1.5 late current (late I(Na)) in generation of arrhythmic activity. The assumption of the authors is that proper Na(+) channel function is necessary to the maintenance of the transmembrane electrochemical gradient of Na(+) and regulation...

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Detalhes bibliográficos
Main Authors: Shryock, John C., Song, Yejia, Rajamani, Sridharan, Antzelevitch, Charles, Belardinelli, Luiz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841414/
https://ncbi.nlm.nih.gov/pubmed/23752976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt145
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