Safety and Immunogenicity of a Gag-Pol Candidate HIV-1 DNA Vaccine Administered by a Needle-Free Device in HIV-1–Seronegative Subjects

OBJECTIVE: To evaluate the safety and immunogenicity of a candidate HIV DNA vaccine administered using a needle-free device. DESIGN: In this phase 1, dose escalation, double-blind, placebo-controlled clinical trial, 21 healthy adults were randomized to receive placebo or 0.5, 1.5, or 4 mg of a singl...

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Main Authors: Tavel, Jorge A., Martin, Julie E., Kelly, Grace G., Enama, Mary E., Shen, Jean M., Gomez, Phillip L., Andrews, Charla A., Koup, Richard A., Bailer, Robert T., Stein, Judy A., Roederer, Mario, Nabel, Gary J., Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365751/
https://ncbi.nlm.nih.gov/pubmed/17325604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3180417cb6
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