Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma

The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor gene spanning the same chromosome region, 16q23, as the second most common fragile site (FS), FRA16D. Deletions detected by comparative genomic hybridisation (CGH) and loss of heterozygosity at microsatellite markers on...

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Bibliographische Detailangaben
Hauptverfasser: Park, S-W, Ludes-Meyers, J, Zimonjic, D B, Durkin, M E, Popescu, N C, Aldaz, C M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Genetics and Genomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364795/
https://ncbi.nlm.nih.gov/pubmed/15266310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602023
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