Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma

The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor gene spanning the same chromosome region, 16q23, as the second most common fragile site (FS), FRA16D. Deletions detected by comparative genomic hybridisation (CGH) and loss of heterozygosity at microsatellite markers on...

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Bibliographic Details
Main Authors: Park, S-W, Ludes-Meyers, J, Zimonjic, D B, Durkin, M E, Popescu, N C, Aldaz, C M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364795/
https://ncbi.nlm.nih.gov/pubmed/15266310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602023
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