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Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma
The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor gene spanning the same chromosome region, 16q23, as the second most common fragile site (FS), FRA16D. Deletions detected by comparative genomic hybridisation (CGH) and loss of heterozygosity at microsatellite markers on...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364795/ https://ncbi.nlm.nih.gov/pubmed/15266310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602023 |
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