Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma

The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor gene spanning the same chromosome region, 16q23, as the second most common fragile site (FS), FRA16D. Deletions detected by comparative genomic hybridisation (CGH) and loss of heterozygosity at microsatellite markers on...

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Main Authors: Park, S-W, Ludes-Meyers, J, Zimonjic, D B, Durkin, M E, Popescu, N C, Aldaz, C M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Genetics and Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364795/
https://ncbi.nlm.nih.gov/pubmed/15266310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602023
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