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WWOX Loss of Function in Neurodevelopmental and Neurodegenerative Disorders

The WWOX gene was initially discovered as a putative tumor suppressor. More recently, its association with multiple central nervous system (CNS) pathologies has been recognized. WWOX biallelic germline pathogenic variants have been implicated in spinocerebellar ataxia type 12 (SCAR12; MIM:614322) an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Aldaz, C. Marcelo, Hussain, Tabish
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727818/
https://ncbi.nlm.nih.gov/pubmed/33255508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238922
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