Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma

The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor gene spanning the same chromosome region, 16q23, as the second most common fragile site (FS), FRA16D. Deletions detected by comparative genomic hybridisation (CGH) and loss of heterozygosity at microsatellite markers on...

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Detalhes bibliográficos
Main Authors: Park, S-W, Ludes-Meyers, J, Zimonjic, D B, Durkin, M E, Popescu, N C, Aldaz, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364795/
https://ncbi.nlm.nih.gov/pubmed/15266310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602023
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