ATM polymorphisms as risk factors for prostate cancer development

The risk of prostate cancer is known to be elevated in carriers of germline mutations in BRCA2, and possibly also in carriers of BRCA1 and CHEK2 mutations. These genes are components of the ATM-dependent DNA damage signalling pathways. To evaluate the hypothesis that variants in ATM itself might be...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Angèle, S, Falconer, A, Edwards, S M, Dörk, T, Bremer, M, Moullan, N, Chapot, B, Muir, K, Houlston, R, Norman, A R, Bullock, S, Hope, Q, Meitz, J, Dearnaley, D, Dowe, A, Southgate, C, Ardern-Jones, A, Easton, D F, Eeles, R A, Hall, J
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2004
Θέματα:
Genetics and Genomics
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364767/
https://ncbi.nlm.nih.gov/pubmed/15280931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602007
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