Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group.

A recent report has provided strong evidence for a major prostate cancer susceptibility locus (HPC1) on chromosome 1q24-25 (Smith et al, 1996). Most inherited cancer susceptibility genes function as tumour-suppressor genes (TSGs). Allelic loss or imbalance in tumour tissue is often the hallmark of a...

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Hlavní autoři: Dunsmuir, W. D., Edwards, S. M., Lakhani, S. R., Young, M., Corbishley, C., Kirby, R. S., Dearnaley, D. P., Dowe, A., Ardern-Jones, A., Kelly, J., Eeles, R. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group|1 1998
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063204/
https://ncbi.nlm.nih.gov/pubmed/9836474
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