No germline mutations in the dimerization domain of MXI1 in prostate cancer clusters. The CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group.

There is evidence that predisposition to cancer has a genetic component. Genetic models have suggested that there is at least one highly penetrant gene predisposing to this disease. The oncogene MXI1 on chromosome band 10q24-25 is mutated in a proportion of prostate tumours and loss of heterozygosit...

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Hlavní autoři: Edwards, S. M., Dearnaley, D. P., Ardern-Jones, A., Hamoudi, R. A., Easton, D. F., Ford, D., Shearer, R., Dowe, A., Eeles, R. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228090/
https://ncbi.nlm.nih.gov/pubmed/9376279
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