Two Percent of Men with Early-Onset Prostate Cancer Harbor Germline Mutations in the BRCA2 Gene

Studies of families with breast cancer have indicated that male carriers of BRCA2 mutations are at increased risk of prostate cancer, particularly at an early age. To evaluate the contribution of BRCA2 mutations to early-onset prostate cancer, we screened the complete coding sequence of BRCA2 for ge...

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Main Authors: Edwards, Stephen M., Kote-Jarai, Zsofia, Meitz, Julia, Hamoudi, Rifat, Hope, Questa, Osin, Peter, Jackson, Rachel, Southgate, Christine, Singh, Rashmi, Falconer, Alison, Dearnaley, David P., Ardern-Jones, Audrey, Murkin, Annette, Dowe, Anna, Kelly, Jo, Williams, Sue, Oram, Richard, Stevens, Margaret, Teare, Dawn M., Ponder, Bruce A. J., Gayther, Simon A., Easton, Doug F., Eeles, Rosalind A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Human Genetics 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC420008/
https://ncbi.nlm.nih.gov/pubmed/12474142
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