HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease

The candidate prostate cancer susceptibility gene HPC2/ELAC2 has two common coding polymorphisms: (Ser→Leu 217) and (Ala→Thr 541). The Thr541 variant in the HPC2/ELAC2 gene has previously been reported to be at an increased frequency in prostate cancer cases. To evaluate this hypothesis we genotyped...

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Detalhes bibliográficos
Main Authors: Meitz, J C, Edwards, S M, Easton, D F, Murkin, A, Ardern-Jones, A, Jackson, R A, Williams, S, Dearnaley, D P, Stratton, M R, Houlston, R S, Eeles, R A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376179/
https://ncbi.nlm.nih.gov/pubmed/12373607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600564
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