ATM polymorphisms as risk factors for prostate cancer development

The risk of prostate cancer is known to be elevated in carriers of germline mutations in BRCA2, and possibly also in carriers of BRCA1 and CHEK2 mutations. These genes are components of the ATM-dependent DNA damage signalling pathways. To evaluate the hypothesis that variants in ATM itself might be...

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Detalhes bibliográficos
Main Authors: Angèle, S, Falconer, A, Edwards, S M, Dörk, T, Bremer, M, Moullan, N, Chapot, B, Muir, K, Houlston, R, Norman, A R, Bullock, S, Hope, Q, Meitz, J, Dearnaley, D, Dowe, A, Southgate, C, Ardern-Jones, A, Easton, D F, Eeles, R A, Hall, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364767/
https://ncbi.nlm.nih.gov/pubmed/15280931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602007
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