Hypermethylation of the 5′ CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis

The Testisin gene (PRSS21) encodes a glycosylphosphatidylinositol (GPI)-linked serine protease that exhibits testis tissue-specific expression. Loss of Testisin has been implicated in testicular tumorigenesis, but its role in testis biology and tumorigenesis is not known. Here we have investigated t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Manton, K J, Douglas, M L, Netzel-Arnett, S, Fitzpatrick, D R, Nicol, D L, Boyd, A W, Clements, J A, Antalis, T M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2005
Pynciau:
Molecular Diagnostics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361880/
https://ncbi.nlm.nih.gov/pubmed/15685234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602373
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