Hypermethylation of the 5′ CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis

The Testisin gene (PRSS21) encodes a glycosylphosphatidylinositol (GPI)-linked serine protease that exhibits testis tissue-specific expression. Loss of Testisin has been implicated in testicular tumorigenesis, but its role in testis biology and tumorigenesis is not known. Here we have investigated t...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Manton, K J, Douglas, M L, Netzel-Arnett, S, Fitzpatrick, D R, Nicol, D L, Boyd, A W, Clements, J A, Antalis, T M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2005
Assuntos:
Molecular Diagnostics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361880/
https://ncbi.nlm.nih.gov/pubmed/15685234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602373
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares