Proteolytic Activation of the Protease-activated Receptor (PAR)-2 by the Glycosylphosphatidylinositol-anchored Serine Protease Testisin

Protease-activated receptors (PARs) are a family of seven-transmembrane, G-protein-coupled receptors that are activated by multiple serine proteases through specific N-terminal proteolytic cleavage and the unmasking of a tethered ligand. The majority of PAR-activating proteases described to date are...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Driesbaugh, Kathryn H., Buzza, Marguerite S., Martin, Erik W., Conway, Gregory D., Kao, Joseph P. Y., Antalis, Toni M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319020/
https://ncbi.nlm.nih.gov/pubmed/25519908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628560
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