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The Glycosylphosphatidylinositol-Anchored Serine Protease PRSS21 (Testisin) Imparts Murine Epididymal Sperm Cell Maturation and Fertilizing Ability

An estimated 25%–40% of infertile men have idiopathic infertility associated with deficient sperm numbers and quality. Here, we identify the membrane-anchored serine protease PRSS21, also known as testisin, to be a novel proteolytic factor that directs epididymal sperm cell maturation and sperm-fert...

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Bibliographic Details
Main Authors: Netzel-Arnett, Sarah, Bugge, Thomas H., Hess, Rex A., Carnes, Kay, Stringer, Brett W., Scarman, Anthony L., Hooper, John D., Tonks, Ian D., Kay, Graham F., Antalis, Toni M.
Format: Artigo
Language:Inglês
Published: Society for the Study of Reproduction, Inc. 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770021/
https://ncbi.nlm.nih.gov/pubmed/19571264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.076273
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