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In vitro selection of self-cleaving RNAs with a low pH optimum

RNAs that undergo a rapid site-specific cleavage at low pH have been selected by in vitro selection (the SELEX process). The cleavage does not require the addition of any divalent metal ions, and is in fact inhibited by divalent metal ions, spermine, or high concentrations of monovalent metal ions....

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Jayasena, Vineetha K., Gold, Larry
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 1997
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380683/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.10612
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