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In vitro selection of self-cleaving RNAs with a low pH optimum

RNAs that undergo a rapid site-specific cleavage at low pH have been selected by in vitro selection (the SELEX process). The cleavage does not require the addition of any divalent metal ions, and is in fact inhibited by divalent metal ions, spermine, or high concentrations of monovalent metal ions....

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Jayasena, Vineetha K., Gold, Larry
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380683/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.10612
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