A cytotoxic ribonuclease which specifically cleaves four isoaccepting arginine tRNAs at their anticodon loops

Colicin D has long been thought to stop protein synthesis in infected Escherichia coli cells by inactivating ribosomes, just like colicin E3. Here, we show that colicin D specifically cleaves tRNAs(Arg) including four isoaccepting molecules both in vivo and in vitro. The cleavage occurs in vitro bet...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Tomita, Kozo, Ogawa, Tetsuhiro, Uozumi, Takeshi, Watanabe, Kimitsuna, Masaki, Haruhiko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.140213797
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