A cytotoxic ribonuclease which specifically cleaves four isoaccepting arginine tRNAs at their anticodon loops

Colicin D has long been thought to stop protein synthesis in infected Escherichia coli cells by inactivating ribosomes, just like colicin E3. Here, we show that colicin D specifically cleaves tRNAs(Arg) including four isoaccepting molecules both in vivo and in vitro. The cleavage occurs in vitro bet...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Tomita, Kozo, Ogawa, Tetsuhiro, Uozumi, Takeshi, Watanabe, Kimitsuna, Masaki, Haruhiko
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.140213797
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!