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The small GTP-binding protein Rho links G protein-coupled receptors and Gα(12 )to the serum response element and to cellular transformation

Receptors coupled to heterotrimeric G proteins can effectively stimulate growth promoting pathways in a large variety of cell types, and if persistently activated, these receptors can also behave as dominant-acting oncoproteins. Consistently, activating mutations for G proteins of the Gα(s) and Gα(i...

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Autores principales: Fromm, Christian, Coso, Omar A., Montaner, Silvia, Xu, Ningzhi, Gutkind, J. Silvio
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC23316/
https://ncbi.nlm.nih.gov/pubmed/9294169
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