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The small GTP-binding protein Rho links G protein-coupled receptors and Gα(12 )to the serum response element and to cellular transformation

Receptors coupled to heterotrimeric G proteins can effectively stimulate growth promoting pathways in a large variety of cell types, and if persistently activated, these receptors can also behave as dominant-acting oncoproteins. Consistently, activating mutations for G proteins of the Gα(s) and Gα(i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fromm, Christian, Coso, Omar A., Montaner, Silvia, Xu, Ningzhi, Gutkind, J. Silvio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC23316/
https://ncbi.nlm.nih.gov/pubmed/9294169
Tagiau: Ychwanegu Tag
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